Diagnosis and management of lymphomas and other cancers in HIV-infected patients.
Identifieur interne : 000260 ( France/Analysis ); précédent : 000259; suivant : 000261Diagnosis and management of lymphomas and other cancers in HIV-infected patients.
Auteurs : Antonino Carbone [Italie] ; Emanuela Vaccher [Italie] ; Annunziata Gloghini [Italie] ; Liron Pantanowitz [États-Unis] ; Akin Abayomi [Afrique du Sud] ; Paolo De Paoli [Italie] ; Silvia Franceschi [France]Source :
- Nature reviews. Clinical oncology [ 1759-4782 ] ; 2014.
Descripteurs français
- KwdFr :
- Agents antiVIH (usage thérapeutique), Association thérapeutique, Détection précoce de cancer, Humains, Infections à VIH (), Lymphocytes T (immunologie), Lymphome lié au SIDA (), Lymphome lié au SIDA (diagnostic), Lymphome lié au SIDA (étiologie), Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique), Sujet immunodéprimé, Survie sans rechute, Thérapie de rattrapage, Thérapie virale de cancers, Transplantation de cellules souches de sang périphérique, Tumeurs (), Tumeurs (diagnostic), Tumeurs (génétique), Virus oncogènes (pathogénicité).
- MESH :
- diagnostic : Lymphome lié au SIDA, Tumeurs.
- génétique : Tumeurs.
- immunologie : Lymphocytes T.
- pathogénicité : Virus oncogènes.
- usage thérapeutique : Agents antiVIH, Protocoles de polychimiothérapie antinéoplasique.
- étiologie : Lymphome lié au SIDA.
- Association thérapeutique, Détection précoce de cancer, Humains, Infections à VIH, Lymphome lié au SIDA, Sujet immunodéprimé, Survie sans rechute, Thérapie de rattrapage, Thérapie virale de cancers, Transplantation de cellules souches de sang périphérique, Tumeurs.
English descriptors
- KwdEn :
- Anti-HIV Agents (therapeutic use), Antineoplastic Combined Chemotherapy Protocols (therapeutic use), Combined Modality Therapy, Disease-Free Survival, Early Detection of Cancer, HIV Infections (complications), Humans, Immunocompromised Host, Lymphoma, AIDS-Related (diagnosis), Lymphoma, AIDS-Related (etiology), Lymphoma, AIDS-Related (therapy), Neoplasms (diagnosis), Neoplasms (genetics), Neoplasms (therapy), Oncogenic Viruses (pathogenicity), Oncolytic Virotherapy, Peripheral Blood Stem Cell Transplantation, Salvage Therapy, T-Lymphocytes (immunology).
- MESH :
- chemical , therapeutic use : Anti-HIV Agents.
- complications : HIV Infections.
- diagnosis : Lymphoma, AIDS-Related, Neoplasms.
- etiology : Lymphoma, AIDS-Related.
- genetics : Neoplasms.
- immunology : T-Lymphocytes.
- pathogenicity : Oncogenic Viruses.
- therapeutic use : Antineoplastic Combined Chemotherapy Protocols.
- therapy : Lymphoma, AIDS-Related, Neoplasms.
- Combined Modality Therapy, Disease-Free Survival, Early Detection of Cancer, Humans, Immunocompromised Host, Oncolytic Virotherapy, Peripheral Blood Stem Cell Transplantation, Salvage Therapy.
Abstract
Despite the introduction of highly active antiretroviral therapy or combination antiretroviral therapy (HAART and cART, respectively) patients infected with HIV might develop certain types of cancer more frequently than uninfected people. Lymphomas represent the most frequent malignancy among patients with HIV. Other cancer types that have increased in these patients include Kaposi sarcoma, cancer of the cervix, anus, lung and liver. In the post-HAART era, however, patients with HIV have experienced a significant improvement in their morbidity, mortality and life expectancy. This Review focuses on the different types of lymphomas that generally occur in patients with HIV. The combination of cART and antineoplastic treatment has resulted in remarkable prolongation of disease-free survival and overall survival among patients with HIV who develop lymphoma. However, the survival in these patients still lags behind that of patients with lymphoma who are not infected with HIV. We also provide an update of epidemiological data, diagnostic issues, and strategies regarding the most-appropriate management of patients with both HIV and lymphomas.
DOI: 10.1038/nrclinonc.2014.31
PubMed: 24614140
Affiliations:
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pubmed:24614140Le document en format XML
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Clinical oncology</title><idno type="eISSN">1759-4782</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-HIV Agents (therapeutic use)</term><term>Antineoplastic Combined Chemotherapy Protocols (therapeutic use)</term><term>Combined Modality Therapy</term><term>Disease-Free Survival</term><term>Early Detection of Cancer</term><term>HIV Infections (complications)</term><term>Humans</term><term>Immunocompromised Host</term><term>Lymphoma, AIDS-Related (diagnosis)</term><term>Lymphoma, AIDS-Related (etiology)</term><term>Lymphoma, AIDS-Related (therapy)</term><term>Neoplasms (diagnosis)</term><term>Neoplasms (genetics)</term><term>Neoplasms (therapy)</term><term>Oncogenic Viruses (pathogenicity)</term><term>Oncolytic Virotherapy</term><term>Peripheral Blood Stem Cell Transplantation</term><term>Salvage Therapy</term><term>T-Lymphocytes (immunology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Agents antiVIH (usage thérapeutique)</term><term>Association thérapeutique</term><term>Détection précoce de cancer</term><term>Humains</term><term>Infections à VIH ()</term><term>Lymphocytes T (immunologie)</term><term>Lymphome lié au SIDA ()</term><term>Lymphome lié au SIDA (diagnostic)</term><term>Lymphome lié au SIDA (étiologie)</term><term>Protocoles de polychimiothérapie antinéoplasique (usage thérapeutique)</term><term>Sujet immunodéprimé</term><term>Survie sans rechute</term><term>Thérapie de rattrapage</term><term>Thérapie virale de cancers</term><term>Transplantation de cellules souches de sang périphérique</term><term>Tumeurs ()</term><term>Tumeurs (diagnostic)</term><term>Tumeurs (génétique)</term><term>Virus oncogènes (pathogénicité)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lymphoma, AIDS-Related</term><term>Neoplasms</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Lymphome lié au SIDA</term><term>Tumeurs</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphoma, AIDS-Related</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Neoplasms</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Tumeurs</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphocytes T</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>T-Lymphocytes</term></keywords><keywords scheme="MESH" qualifier="pathogenicity" xml:lang="en"><term>Oncogenic Viruses</term></keywords><keywords scheme="MESH" qualifier="pathogénicité" xml:lang="fr"><term>Virus oncogènes</term></keywords><keywords scheme="MESH" qualifier="therapeutic use" xml:lang="en"><term>Antineoplastic Combined Chemotherapy Protocols</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphoma, AIDS-Related</term><term>Neoplasms</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents antiVIH</term><term>Protocoles de polychimiothérapie antinéoplasique</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphome lié au SIDA</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Combined Modality Therapy</term><term>Disease-Free Survival</term><term>Early Detection of Cancer</term><term>Humans</term><term>Immunocompromised Host</term><term>Oncolytic Virotherapy</term><term>Peripheral Blood Stem Cell Transplantation</term><term>Salvage Therapy</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Association thérapeutique</term><term>Détection précoce de cancer</term><term>Humains</term><term>Infections à VIH</term><term>Lymphome lié au SIDA</term><term>Sujet immunodéprimé</term><term>Survie sans rechute</term><term>Thérapie de rattrapage</term><term>Thérapie virale de cancers</term><term>Transplantation de cellules souches de sang périphérique</term><term>Tumeurs</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite the introduction of highly active antiretroviral therapy or combination antiretroviral therapy (HAART and cART, respectively) patients infected with HIV might develop certain types of cancer more frequently than uninfected people. Lymphomas represent the most frequent malignancy among patients with HIV. Other cancer types that have increased in these patients include Kaposi sarcoma, cancer of the cervix, anus, lung and liver. In the post-HAART era, however, patients with HIV have experienced a significant improvement in their morbidity, mortality and life expectancy. This Review focuses on the different types of lymphomas that generally occur in patients with HIV. The combination of cART and antineoplastic treatment has resulted in remarkable prolongation of disease-free survival and overall survival among patients with HIV who develop lymphoma. However, the survival in these patients still lags behind that of patients with lymphoma who are not infected with HIV. We also provide an update of epidemiological data, diagnostic issues, and strategies regarding the most-appropriate management of patients with both HIV and lymphomas.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>France</li><li>Italie</li><li>États-Unis</li></country></list><tree><country name="Italie"><noRegion><name sortKey="Carbone, Antonino" sort="Carbone, Antonino" uniqKey="Carbone A" first="Antonino" last="Carbone">Antonino Carbone</name></noRegion><name sortKey="De Paoli, Paolo" sort="De Paoli, Paolo" uniqKey="De Paoli P" first="Paolo" last="De Paoli">Paolo De Paoli</name><name sortKey="Gloghini, Annunziata" sort="Gloghini, Annunziata" uniqKey="Gloghini A" first="Annunziata" last="Gloghini">Annunziata Gloghini</name><name sortKey="Vaccher, Emanuela" sort="Vaccher, Emanuela" uniqKey="Vaccher E" first="Emanuela" last="Vaccher">Emanuela Vaccher</name></country><country name="États-Unis"><noRegion><name sortKey="Pantanowitz, Liron" sort="Pantanowitz, Liron" uniqKey="Pantanowitz L" first="Liron" last="Pantanowitz">Liron Pantanowitz</name></noRegion></country><country name="Afrique du Sud"><noRegion><name sortKey="Abayomi, Akin" sort="Abayomi, Akin" uniqKey="Abayomi A" first="Akin" last="Abayomi">Akin Abayomi</name></noRegion></country><country name="France"><noRegion><name sortKey="Franceschi, Silvia" sort="Franceschi, Silvia" uniqKey="Franceschi S" first="Silvia" last="Franceschi">Silvia Franceschi</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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